Quick and Easy Test for

Blood Rheology

Innovative Technology for Hemorheology

Model: RheoSCAN-D500

RheoSCAN-AnD300 can measure comprehensive rheological properties of blood within a short time (< 2 min). Now, RBC deformability, aggregation and aggregating force can be easily measured with a leading-edge microfluidic technology.

• Deformability : EI@3Pa, EImax, t1/2
• Aggregation : AI, M, ESR, t1/2
• Aggregating force : critical shear stress (CSS)
• Due to the quick and easy operation, RheoSCAN can be used at research laboratories and clinical environments.

RBC Deformability
- Sample volume :5㎕
- Testing Time : 30 s
- Microfluidic

- Laser Diffraction

RBC Aggregation
- Sample volume : 8㎕
- Testing time : 120 s
- Microfluidic Stirring

- Light Transmission

Critical Shear Stress

- Sample volume : 500㎕ (=0.5mL)
- Testing Time : 30 s
- Microfluidic shearing

- Light Backscattering

Introducing RheoSCAN

diabetic complication early diagnosis rheoscan

FAST

Rapid test: the test takes less than a minute (30~60 seconds)

WHOLE BLOOD

Small volume of whole blood needed
Deformability(EI): 6uL + PVP Sol.
Critical Shear Stress(CSS): 500uL

SIMPLE & EASY

One step of pipetting
Disposable microchip
Automated operation

INNOVATIVE

The core technology includes:

Laser-diffraction
Microfluidic Rheometry
Image analysis
Precision fabrication

TARGETED

Patients with:

Diabetes Mellitus
Diabetic Complications
Diabetic Retinopathy (eye)
Diabetic Nephropathy (kidney)
Metabolic Syndrome
Anyone who want's to check their health status

EARLY DETECTION

RheoScan system shows significantly high correlation with DKD, DR, and MetS through CSS

Diabetic Complication Screening Assay - RheoSCAN-D300

RBC Deformability

hematology analyzer RheoSCAN RBC Deformability3

Laser-Diffraction

*RheoScan AnD-300

*RheoScan D-300

Cytometry Part B (2006)

Biosensor &Bioelectronics (2003)

(X=L, Y=W)

Cytometry Part B (2006)

Impaired RBC Deformability leads to hypoxia

RBC deformability plays a critical role in blood circulation. Healthy RBCs have to pass through capillaries whose diameter is smaller than their size. Decreased red blood cell deformability results in hypoxia due to decreased oxygen delivery capacity in blood vessels.

→ Serious problem in micro-circulation

Hyper-aggregated RBCs result in vascular diseases

RBC aggregation is one of the key factors in determining blood flow resistance in microcirculation. Healthy red blood cells are easy to disaggregate and enter small vessels in an efficient manner, whereas hyper-aggregated red blood cells do not dis-aggregate and causes local hypertension, vascular sclerosis, and hypoxia.

Innovative Microfluidic Diffractometer Standard comparison